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Madelung's deformity Clinodactyly Oligodactyly Polydactyly.
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| Crypto dysplasia | ICD - 10 : Q Based on symptoms and X-rays , confirmed by genetic testing [4]. Sibling actress-singers Milly [27] and Abby Shapiro were born with cleidocranial dysplasia, a trait they share with their mother. For permissions, please email: journals. Autoimmune polyendocrine syndrome type 1. |
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| La arenas | Individuals with cleidocranial dysplasia often have decreased bone density osteopenia and may develop osteoporosis , a condition that makes bones progressively more brittle and prone to fracture, at a relatively early age. Delayed maturation of the skull cranium is also characteristic of this condition, including delayed closing of the growth lines where the bones of the skull meet sutures and larger than normal spaces fontanelles between the skull bones that are noticeable as "soft spots" on the heads of infants. Researchers believe that the RUNX2 protein acts as a "master switch," regulating a number of other genes involved in the development of cells that build bones osteoblasts and in the development of teeth. Cleidocranial dysplasia: Clinical, endocrinologic and molecular findings in 15 patients from 11 families. Wikimedia Commons. |
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